W. Xu
Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences – Beijing, China

Objective: We aim to investigate the feasibility of real-time TCD-EEG monitoring in patients with paroxysmal neurological diseases.

Design and Methods: This is an on-going single-center observational study. Six hours Real-time TCD-EEG (Delica NSD-8100) is performed in pre-surgical patients with refractory epilepsy and pre-surgical patients with Moyamoya disease and transient ischemic attacks. The TCD-EEG monitoring includes 10-20 system 16 channels EEG and bilateral middle cerebral artery blood flow velocity (CBFV) monitoring. To further investigate TCD value in the localization of epileptogenic focus, SPECT is performed, if available, in patients with seizure attacks for comparative analysis. To induce transient ischemic attacks, 3 minutes hyperventilation is performed in patients with Moyamoya disease.